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From peas to "chips" – the new millennium of molecular biology: a primer for the surgeon

Iain Brown email, Steven D Heys email and Andrew C Schofield email

Section of Surgical Oncology, Department of Surgery, University Medical School Buildings, University of Aberdeen, Aberdeen, UK, AB25 2ZD

author email corresponding author email

World Journal of Surgical Oncology 2003, 1:21doi:10.1186/1477-7819-1-21

Published: 21 October 2003

First paragraph (this article has no abstract)

The mechanisms underlying the basis of heredity and the beginning of understanding of the genetic basis of life began to be unravelled some 160 years ago. These fundamental concepts, which have paved the way for the current explosion in our understanding of the genetic basis of cellular function, were established from the study of pea plants by an Augustinian monk, Gregor Mendel. The next major development in genetics was 100 years later when Watson and Crick discovered the structure of DNA. Following on from their seminal work there has been an exponential growth in knowledge regarding the structure and function of DNA and its functional unit, the gene [1].


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