Table 2

Molecular factors involved in progression in PanCa cells related to diabetes
Molecules Expression levels Role in PanCa Refs
IGF-1 and receptor Increased Increase the risk and worse survival [35,36]
14-amino-acid peptide from S100A8 Increased Promote the growth of PanCa by activating Akt and NF-κB signaling [38,39]
Regenerating gene I alpha protein Increased Accelerated cell proliferation [40]
Increased Predictors of poor survival [41]
Increased Contribute to determining diabetes [42]

IGF-1, insulin-like growth factor 1; PanCa, pancreatic cancer.

Li et al.

Li et al. World Journal of Surgical Oncology 2012 10:171   doi:10.1186/1477-7819-10-171

Open Data