Primary yolk sac tumor of seminal vesicle: a case report and literature review
- Equal contributors
1 Department of Urology, Fudan University Shanghai Cancer Center, 270 Dong’an Road, Shanghai, 200032, China
2 Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
3 Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
World Journal of Surgical Oncology 2012, 10:189 doi:10.1186/1477-7819-10-189Published: 14 September 2012
Yolk sac tumor (endodermal sinus tumor) is a rare malignant germ cell tumor arising in the testis or ovary. Extragonadal yolk sac tumor is even rarer and has only been described in case reports. Due to the rarity of the tumors, the appropriately optimal treatment remains unclear. We report a case of yolk sac tumor in the seminal vesicle.
A 38-year-old Asian male presented with gross hematuria and hemospermia. Transrectal ultrasound scan showed a solid mass in the left seminal vesicle and the scrotal sonography showed no abnormalities. Bilateral seminal vesicles were resected, and histopathological examination showed a typical pattern of yolk sac tumor (YST). The patient responded poorly to comprehensive treatment of radiotherapy, chemotherapy and surgeries, developed systemic multiple metastases, and died of cachexia one and half years after diagnosis.