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Clinical practice guidelines for patients with gastrointestinal stromal tumor in Taiwan

Chun-Nan Yeh1, Tsann-Long Hwang1, Ching-Shui Huang1, Po-Huang Lee2, Chew-Wun Wu3, Ker Chen-Guo4, Yi-Yin Jan1, Miin-Fu Chen1* and On behalf of Taiwan Surgical Society of Gastroenterology

Author Affiliations

1 Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, #5, Fu-Hsing Street Kwei-Shan, Taoyuan, Taiwan

2 Department of Surgery, National Taiwan University Hospital, Taipei, 100, Taiwan

3 Department of Surgery, Taipei Veteran General Hospital, Taipei, 100, Taiwan

4 Department of Surgery, Yuan’s General Hospital, Kaohsiung City, Taiwan

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World Journal of Surgical Oncology 2012, 10:246  doi:10.1186/1477-7819-10-246

Published: 15 November 2012


For many years, the understanding of gastrointestinal stromal tumors (GISTs), which are the most common mesenchymal tumors of the gastrointestinal tract, has been very limited. However, it is now possible to provide a more precise definition through the use of pathology classification and molecular techniques. Coupled with the advancement of clinical practice, especially the development of targeted therapy, there is now a much better insight into its treatment. At present, organizations such as the National Comprehensive Cancer Network in the USA and the European Society for Medical Oncology in Europe have established a consensus and drawn up guidelines for the diagnosis, treatment, and follow-up of GISTs.

With experts coming from various districts in Taiwan and combining the most recent clinical data and experiences, the Taiwan Surgical Society of Gastroenterology drafted the first national GIST treatment guidelines after a consensus meeting in 2007. Following subsequent advances in GIST diagnosis and treatment, further revisions and modifications have been made to the original guidelines. We present here the updated consensus and recommendations of the Taiwan Surgical Society of Gastroenterology for the diagnosis and treatment of GIST. We hope these guidelines can help enhance the quality of diagnosis, treatment, and care of patients with GIST in Taiwan.

Guidelines; Gastrointestinal stromal tumors; Imatinib; Targeted; Treatment