|
Immunohistochemistry and Mutations in the primary omental GISTs |
||||||||
| Case No. |
Histology |
Immunohistochemistry |
Mutations |
|||||
|
|
||||||||
| KIT |
CD34 |
S100 |
SMA |
Desmin |
Gene |
Site |
||
|
|
||||||||
| 15 |
Spindle |
Positive |
+ |
- |
- |
- |
C-kit |
Exon11, MS |
| 16 |
Spindle |
Positive |
+ |
- |
- |
- |
C-kit |
Exon11, IFD |
| 17 |
Spindle |
Positive |
+ |
- |
- |
- |
C-kit |
Exon11, MS |
| 18 |
Spindle |
Positive |
+ |
- |
- |
- |
C-kit |
Exon11, MS |
| 19 |
Spindle |
Positive |
+ |
- |
Weak |
- |
C-kit |
Exon11, IFD |
| 22 |
Myxoid epithelioid |
Weak |
+ |
- |
+ |
- |
PDGFRA |
Exon18 del D842V |
| 23 |
Epithelioid |
Weak |
- |
- |
- |
- |
PDGFRA |
Exon18 DIMH842-845 |
| 26 |
Epithelioid |
Weak |
+ |
NA |
NA |
NA |
PDGFRA |
Exon18 |
| 28 |
Myxoid epithelioid |
Weak |
+ |
- |
- |
- |
PDGFRA |
Exon12, V561D |
|
MS: miss sense, IFD: in-frame deletion, NA: not available | ||||||||
Todoroki et al. World Journal of Surgical Oncology 2007 5:66 doi:10.1186/1477-7819-5-66 |
||||||||