"Pseudosarcoma" in a pregnant woman
Royal Free and University College London Hospitals, Royal National Orthopaedic Hospital, Bone Tumour Unit, Brockley Hill, Stanmore, Middlesex, HA7 4L, UK
World Journal of Surgical Oncology 2007, 5:7 doi:10.1186/1477-7819-5-7Published: 18 January 2007
Intravascular fasciitis (IVF) is a rare benign condition characterised by reactive myofibroblastic proliferation arising from the superficial or deep fascia and involving arteries and/or veins. It is a distinct variant of the more common condition of nodular fasciitis, which possesses similar clinical and histological features to IVF, but lacks vascular invasion. A thorough review of the literature revealed 26 reported cases of IVF.
We report a case of IVF in a 16-week pregnant lady affecting the hypothenar eminence of the hand associated with the ulnar artery.
The characteristic involvement of muscular arteries and veins by reactive myofibroblastic proliferation in IVF suggests a malignant component and often leads to an inappropriate diagnosis for this benign condition. We propose that hormone-related changes associated with pregnancy may play an important role in the aetiopathogenesis of this myofibroblastic lesion.