Table 1

Main morphological features of mesenchymal lesions of the breast

Tumor type
atypia
vascular component
hemorrhage
necrosis
mitoses
CK
EMA
Vim
CD34
Bcl2
CD99
actin
desmin
S100

Solitary fibrous tumor
no
prominent
no
no
rare
-/+
+/-
+
+
+
+
-/+
-/+
-/+
Myofibroblastoma
no
present
no
no
rare
-
-
+
+/-
+/-
+/-
+
+
-
Fibromatosis
no
scarce
no
no
rare
-

+



-/+
-
-
Hemangiopericytoma
mild
abundant
no
rare
variable


+
+/-

+/-
-/+
-/+

Nodular fascitis
no
abundant
red cell extravasion
no
present
-





+
+/-
-
Inflammatory myofibroblastic tumor *
mild
abundant
no
no

-/+

+



+/-
+
-
Leiomyoma
no
normal
no
no
rare
-
-
+
-
-
-
+
+
-
Metaplastic carcinoma
yes
normal
no
rare
present
+
-/+
+
-


+

-
Myoepithelioma
mild
normal
no
no
present
+


-


+
-
+
Pseudoangiomatous stromal hyperplasia
no
pseudovascular spaces
no
no
no
-
-
+
+
-
-
+
-
-

CK: cytokeratin; EMA: epithelial membrane antigen; Vim: vimentin; *: ALK positive

Rovera et al. World Journal of Surgical Oncology 2008 6:16   doi:10.1186/1477-7819-6-16