|
Main morphological features of mesenchymal lesions of the breast |
||||||||||||||
| Tumor type |
atypia |
vascular component |
hemorrhage |
necrosis |
mitoses |
CK |
EMA |
Vim |
CD34 |
Bcl2 |
CD99 |
actin |
desmin |
S100 |
|
|
||||||||||||||
| Solitary fibrous tumor |
no |
prominent |
no |
no |
rare |
-/+ |
+/- |
+ |
+ |
+ |
+ |
-/+ |
-/+ |
-/+ |
| Myofibroblastoma |
no |
present |
no |
no |
rare |
- |
- |
+ |
+/- |
+/- |
+/- |
+ |
+ |
- |
| Fibromatosis |
no |
scarce |
no |
no |
rare |
- |
+ |
-/+ |
- |
- |
||||
| Hemangiopericytoma |
mild |
abundant |
no |
rare |
variable |
+ |
+/- |
+/- |
-/+ |
-/+ |
||||
| Nodular fascitis |
no |
abundant |
red cell extravasion |
no |
present |
- |
+ |
+/- |
- |
|||||
| Inflammatory myofibroblastic tumor * |
mild |
abundant |
no |
no |
-/+ |
+ |
+/- |
+ |
- |
|||||
| Leiomyoma |
no |
normal |
no |
no |
rare |
- |
- |
+ |
- |
- |
- |
+ |
+ |
- |
| Metaplastic carcinoma |
yes |
normal |
no |
rare |
present |
+ |
-/+ |
+ |
- |
+ |
- |
|||
| Myoepithelioma |
mild |
normal |
no |
no |
present |
+ |
- |
+ |
- |
+ |
||||
| Pseudoangiomatous stromal hyperplasia |
no |
pseudovascular spaces |
no |
no |
no |
- |
- |
+ |
+ |
- |
- |
+ |
- |
- |
|
CK: cytokeratin; EMA: epithelial membrane antigen; Vim: vimentin; *: ALK positive | ||||||||||||||
Rovera et al. World Journal of Surgical Oncology 2008 6:16 doi:10.1186/1477-7819-6-16 |
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