Case report

Cutaneous skull metastasis from uterine leiomyosarcoma: a case report

Nikolaos Barbetakis¹ , Dimitrios Paliouras¹ , Christos Asteriou¹ , Georgios Samanidis¹ , Athanassios Kleontas² , Doxakis Anestakis³ , Kostas Kaplanis⁴ and Christodoulos Tsilikas¹

¹  Thoracic Surgery Department, Theagenio Cancer Hospital, A. Simeonidi 2, Thessaloniki, 54007, Greece

²  General Surgery Department, Theagenio Cancer Hospital, A. Simeonidi 2, Thessaloniki, 54007, Greece

³  Pathology Department, Theagenio Cancer Hospital, A. Simeonidi 2, Thessaloniki, 54007, Greece

⁴  Gynecology Department, Theagenio Cancer Hospital, A. Simeonidi 2, Thessaloniki, 54007, Greece

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World Journal of Surgical Oncology 2009, 7:45doi:10.1186/1477-7819-7-45

Published:	11 May 2009

Abstract

Background

Cutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer.

Case presentation

A 52-year-old woman who admitted with a lung and a skull skin nodule is presented. She had a known diagnosis of uterine leiomyosarcoma following an extended total hysterectomy two years ago. Excision biopsy of both nodules revealed metastatic disease.

Conclusion

The appearance of a cutaneous nodule in a patient with a history of uterine leiomyosarcoma might indicate a metastatic tumor lesion. Biopsy and immunohistochemistry are essential for correct diagnosis.