Secondary malignancy of the thyroid gland: a case report and review of the literature.
Haugen BR, Nawaz S, Cohn A, Shroyer K, Bunn PA Jr, Liechty DR, Ridgway EC.
Division of Endocrinology, University of Colorado Health Sciences Center, Denver 80262.
Metastatic cancer to the thyroid gland is uncommon. In this report we describe a patient with a malignant fibrous histiocytoma that metastasized to the thyroid, possibly to a preexisting thyroid nodule. A review of the literature reveals that breast and lung carcinoma are the most frequently identified sources of secondary thyroid carcinoma found at autopsy, while renal carcinoma comprises over 50% of secondary thyroid malignancies discovered clinically. A number of authors suggest that preexisting thyroid disease (i.e., multinodular goiter and thyroid nodules) may provide a nidus for metastases to the thyroid gland.
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PMID: 7833666 [PubMed - indexed for MEDLINE]