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Table 1
The potential mechanisms of diabetes in PanCa
Parameters		Role in PanCa	Refs
Pancreatic duct	Enlargement	Mechanical obstruction	[24]
	Replication increased	Predisposing factor	[25]
Hyperinsulinism and insulin resistance	Post-insulin receptor defect	Impaired glycogen synthesis and storage	[27]
	Plasma glucagon levels and IAPP	Early development of PanCa	[28]
	Polymorphism of -23HphI (A/T)	Pathogenesis of PanCa	[29]
Tumor size	Increased	Decreased postresection survival	[31]
		Enhanced growth	[32]
Genetic variants	HK2 R844K GA/AA genotype	Increased risk	[33]
	K-ras codon 12 mutations	Increased risk	[34]

IAPP, islet amyloid polypeptide; PanCa, pancreatic cancer.

Li et al. World Journal of Surgical Oncology 2012 10:171 doi:10.1186/1477-7819-10-171

Table 1